anti mat2a Search Results


mat2a antibody - bsa free  (Bio-Techne corporation)
94
Bio-Techne corporation mat2a antibody - bsa free
Mat2a Antibody Bsa Free, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+mat2a/MAT2A+Antibody+-+BSA+Free/custom%40nb110-94158%4010%2E7554%2Felife%2E64930
Average 94 stars, based on 1 article reviews
mat2a antibody - bsa free - by Bioz Stars, 2026-10
94/100 stars
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rabbit anti mat2a polyclonal affinity purified  (Innovative Research Inc)
N/A
Rabbit Anti MAT2A Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50%
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rabbit anti mat2a  (Atlas Antibodies)
91
Atlas Antibodies rabbit anti mat2a
Rabbit Anti Mat2a, supplied by Atlas Antibodies, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+mat2a/Anti-MAT2A/pm36975381-177-8-10
Average 91 stars, based on 1 article reviews
rabbit anti mat2a - by Bioz Stars, 2026-10
91/100 stars
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anti-mat2a (gtx50027)  (GeneTex)
90
GeneTex anti-mat2a (gtx50027)
Anti Mat2a (Gtx50027), supplied by GeneTex, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+mat2a/anti+mat2a/us11872230-299-5-8
Average 90 stars, based on 1 article reviews
anti-mat2a (gtx50027) - by Bioz Stars, 2026-10
90/100 stars
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anti-mat2a (cat. no. r389369)  (ZenBio)
90
ZenBio anti-mat2a (cat. no. r389369)
The new SUMO E1 CAIs perturb polyamine synthesis through the <t>MAT2A-AdoMetDC</t> axis. (a) MAT2A is a SUMOylation substrate and converts methionine (Met) to S-adenosylmethionine (AdoMet). AdoMetDC decarboxylates AdoMet to produce dcAdoMet for the synthesis of spermidine (Spd) and spermine (Spm). ODC decarboxylates ornithine (Orn) to generate putrescine (Put). (b) The cellular level of MAT2A was assessed with Western blotting after T47D cells were treated with the CAIs. (c) The cellular level of AdoMet was assessed with LC-MS after T47D cells were treated with the CAIs. (d) The cellular levels of polyamines were assessed with LC-MS after T47D cells were treated with the CAIs. (e) The cellular levels of two rate-limiting polyamine synthesis enzymes, ODC and AdoMetDC, were assessed with Western blotting after T47D cells were treated with the CAIs.
Anti Mat2a (Cat. No. R389369), supplied by ZenBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+mat2a/anti+MAT2A++Cat++NO++R389369/bio_rxiv__2024__12__12__627095-152-8-15
Average 90 stars, based on 1 article reviews
anti-mat2a (cat. no. r389369) - by Bioz Stars, 2026-10
90/100 stars
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rabbit anti mat2a  (Boster Bio)
94
Boster Bio rabbit anti mat2a
The new SUMO E1 CAIs perturb polyamine synthesis through the <t>MAT2A-AdoMetDC</t> axis. (a) MAT2A is a SUMOylation substrate and converts methionine (Met) to S-adenosylmethionine (AdoMet). AdoMetDC decarboxylates AdoMet to produce dcAdoMet for the synthesis of spermidine (Spd) and spermine (Spm). ODC decarboxylates ornithine (Orn) to generate putrescine (Put). (b) The cellular level of MAT2A was assessed with Western blotting after T47D cells were treated with the CAIs. (c) The cellular level of AdoMet was assessed with LC-MS after T47D cells were treated with the CAIs. (d) The cellular levels of polyamines were assessed with LC-MS after T47D cells were treated with the CAIs. (e) The cellular levels of two rate-limiting polyamine synthesis enzymes, ODC and AdoMetDC, were assessed with Western blotting after T47D cells were treated with the CAIs.
Rabbit Anti Mat2a, supplied by Boster Bio, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+mat2a/Anti-MAT2A+Antibody/pm40517800-74-11-15
Average 94 stars, based on 1 article reviews
rabbit anti mat2a - by Bioz Stars, 2026-10
94/100 stars
  Buy from Supplier
mat2a antibody (3a2) - bsa free  (Bio-Techne corporation)
94
Bio-Techne corporation mat2a antibody (3a2) - bsa free
The new SUMO E1 CAIs perturb polyamine synthesis through the <t>MAT2A-AdoMetDC</t> axis. (a) MAT2A is a SUMOylation substrate and converts methionine (Met) to S-adenosylmethionine (AdoMet). AdoMetDC decarboxylates AdoMet to produce dcAdoMet for the synthesis of spermidine (Spd) and spermine (Spm). ODC decarboxylates ornithine (Orn) to generate putrescine (Put). (b) The cellular level of MAT2A was assessed with Western blotting after T47D cells were treated with the CAIs. (c) The cellular level of AdoMet was assessed with LC-MS after T47D cells were treated with the CAIs. (d) The cellular levels of polyamines were assessed with LC-MS after T47D cells were treated with the CAIs. (e) The cellular levels of two rate-limiting polyamine synthesis enzymes, ODC and AdoMetDC, were assessed with Western blotting after T47D cells were treated with the CAIs.
Mat2a Antibody (3a2) Bsa Free, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+mat2a/MAT2A+Antibody+(3A2)+-+BSA+Free/bio-techne+corporation___nbp1-28605
Average 94 stars, based on 1 article reviews
mat2a antibody (3a2) - bsa free - by Bioz Stars, 2026-10
94/100 stars
  Buy from Supplier
mat2a antibody  (Bio-Techne corporation)
93
Bio-Techne corporation mat2a antibody
The new SUMO E1 CAIs perturb polyamine synthesis through the <t>MAT2A-AdoMetDC</t> axis. (a) MAT2A is a SUMOylation substrate and converts methionine (Met) to S-adenosylmethionine (AdoMet). AdoMetDC decarboxylates AdoMet to produce dcAdoMet for the synthesis of spermidine (Spd) and spermine (Spm). ODC decarboxylates ornithine (Orn) to generate putrescine (Put). (b) The cellular level of MAT2A was assessed with Western blotting after T47D cells were treated with the CAIs. (c) The cellular level of AdoMet was assessed with LC-MS after T47D cells were treated with the CAIs. (d) The cellular levels of polyamines were assessed with LC-MS after T47D cells were treated with the CAIs. (e) The cellular levels of two rate-limiting polyamine synthesis enzymes, ODC and AdoMetDC, were assessed with Western blotting after T47D cells were treated with the CAIs.
Mat2a Antibody, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+mat2a/MAT2A+Antibody/bio-techne+corporation___nbp1-92100
Average 93 stars, based on 1 article reviews
mat2a antibody - by Bioz Stars, 2026-10
93/100 stars
  Buy from Supplier
anti-mat2a rabbit monoclonal antibody  (Boster Bio)
N/A
Boster Bio Anti-MAT2A Rabbit Monoclonal Antibody catalog # M04557. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
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rabbit anti-human mat2a (aa26-55)  (RayBiotech)
N/A
MAT2A Rabbit anti-Human Polyclonal (aa26-55) (Unconjugated) Antibody, (200µl)
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anti-mat2a monoclonal antibody, clone mafb4208  (Creative BioMart)
N/A
Methionine adenosyltransferase II (MAT II) is a key enzyme in cellular metabolism and catalyzes the formation of S-adenosylmethionine (SAMe) from L-methionine and ATP. MAT2A is expressed in extrahepatic tissues. In liver, MAT2A expression associates with
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rabbit anti-human mat2a polyclonal antibody  (Cusabio)
N/A
Rabbit anti-Human MAT2A Polyclonal Antibody
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Image Search Results


The new SUMO E1 CAIs perturb polyamine synthesis through the MAT2A-AdoMetDC axis. (a) MAT2A is a SUMOylation substrate and converts methionine (Met) to S-adenosylmethionine (AdoMet). AdoMetDC decarboxylates AdoMet to produce dcAdoMet for the synthesis of spermidine (Spd) and spermine (Spm). ODC decarboxylates ornithine (Orn) to generate putrescine (Put). (b) The cellular level of MAT2A was assessed with Western blotting after T47D cells were treated with the CAIs. (c) The cellular level of AdoMet was assessed with LC-MS after T47D cells were treated with the CAIs. (d) The cellular levels of polyamines were assessed with LC-MS after T47D cells were treated with the CAIs. (e) The cellular levels of two rate-limiting polyamine synthesis enzymes, ODC and AdoMetDC, were assessed with Western blotting after T47D cells were treated with the CAIs.

Journal: bioRxiv

Article Title: SUMO E1 covalent allosteric inhibitors modulate polyamine synthesis via the MAT2A-AdoMetDC axis

doi: 10.1101/2024.12.12.627095

Figure Lengend Snippet: The new SUMO E1 CAIs perturb polyamine synthesis through the MAT2A-AdoMetDC axis. (a) MAT2A is a SUMOylation substrate and converts methionine (Met) to S-adenosylmethionine (AdoMet). AdoMetDC decarboxylates AdoMet to produce dcAdoMet for the synthesis of spermidine (Spd) and spermine (Spm). ODC decarboxylates ornithine (Orn) to generate putrescine (Put). (b) The cellular level of MAT2A was assessed with Western blotting after T47D cells were treated with the CAIs. (c) The cellular level of AdoMet was assessed with LC-MS after T47D cells were treated with the CAIs. (d) The cellular levels of polyamines were assessed with LC-MS after T47D cells were treated with the CAIs. (e) The cellular levels of two rate-limiting polyamine synthesis enzymes, ODC and AdoMetDC, were assessed with Western blotting after T47D cells were treated with the CAIs.

Article Snippet: The rabbit monoclonal anti-RanGAP1 (Cat. NO. R383099) and anti-MAT2A (Cat. NO. R389369) antibodies were from ZenBio, Inc. (U.S.A.).

Techniques: Western Blot, Liquid Chromatography with Mass Spectroscopy

The new SUMO E1 CAIs synergize with the AdoMetDC inhibitor in inhibiting cancer cells. (a) High MAT2A expression was associated with low recurrence-free survival probability in Luminal A breast cancer patients. The data were obtained from DepMap ( https://depmap.org/portal/ ). (b) The MAT2A CRISPR Dependence Scores (CRISPR (DepMap Public 24Q2+Score, Chronos)) of the top ten cancer types were retrieved from the DepMap . The red dotted line (−1) indicates the median Gene Effect (Chronos) −1. The case numbers are shown on the right. (c) The new CAIs inhibited the proliferation and growth of T47D cells. (d) The new CAIs inhibited the migration of T47D cells. For MCULE-3064932370: high, 25 μM; low: 12.5 μM. For MCULE-6830015021: high, 10 μM; low: 5 μM. (e) The new CAIs synergized with MGBG in inhibiting the proliferation and growth of T47D cells. (f) The comparison of the proteomic changes when T47D cells were treated by MCULE-3064932370 (20 μM) and MCULE-6830015021 (10 μM). Blue dots: upregulated by MCULE-3064932370; green dots: upregulated by MCULE-6830015021; red dot: downregulated by both.

Journal: bioRxiv

Article Title: SUMO E1 covalent allosteric inhibitors modulate polyamine synthesis via the MAT2A-AdoMetDC axis

doi: 10.1101/2024.12.12.627095

Figure Lengend Snippet: The new SUMO E1 CAIs synergize with the AdoMetDC inhibitor in inhibiting cancer cells. (a) High MAT2A expression was associated with low recurrence-free survival probability in Luminal A breast cancer patients. The data were obtained from DepMap ( https://depmap.org/portal/ ). (b) The MAT2A CRISPR Dependence Scores (CRISPR (DepMap Public 24Q2+Score, Chronos)) of the top ten cancer types were retrieved from the DepMap . The red dotted line (−1) indicates the median Gene Effect (Chronos) −1. The case numbers are shown on the right. (c) The new CAIs inhibited the proliferation and growth of T47D cells. (d) The new CAIs inhibited the migration of T47D cells. For MCULE-3064932370: high, 25 μM; low: 12.5 μM. For MCULE-6830015021: high, 10 μM; low: 5 μM. (e) The new CAIs synergized with MGBG in inhibiting the proliferation and growth of T47D cells. (f) The comparison of the proteomic changes when T47D cells were treated by MCULE-3064932370 (20 μM) and MCULE-6830015021 (10 μM). Blue dots: upregulated by MCULE-3064932370; green dots: upregulated by MCULE-6830015021; red dot: downregulated by both.

Article Snippet: The rabbit monoclonal anti-RanGAP1 (Cat. NO. R383099) and anti-MAT2A (Cat. NO. R389369) antibodies were from ZenBio, Inc. (U.S.A.).

Techniques: Expressing, CRISPR, Migration, Comparison